Duchenne Muscular Dystrophy (DMD)

Duchenne Muscular Dystrophy (DMD) is severe genetic disorder affecting the muscles. It is caused by a mutation of the DMD gene that leads to the loss of functional dystrophin, an important protein in muscle cell durability. Symptoms appear early in life, and are devastating, resulting in muscle wasting, loss of mobility at a young age, and eventually death, usually during young adulthood. The purpose of these pages is to look into the literature of DMD, and examine various themes in our understanding of the disease and the systems it impacts.

Table of Contents

Normal Function: Dystrophin and the Muscular System

Discovering DMD – Identification and Distinction

Biochemical And Cellular Pathology Of DMD